Human Mammary Epithelial Cell Line

An overview of growth aging senescence and immortality.

Human mammary epithelial cell line.

Definition of epithelial cells. Additional websites of interest for mammary gland biology. Not detected bacteria yeast and othe. To overcome this problem we have developed a cell line that was immortalized using defined genetic elements and we have characterized this immortalized non tumorigenic human mammary epithelial cell line to establish it as a potential model system.

A mammary gland is an exocrine gland in humans and other mammals that produces milk to feed young offspring mammals get their name from the latin word mamma breast the mammary glands are arranged in organs such as the breasts in primates for example humans and chimpanzees the udder in ruminants for example cows goats and deer and the dugs of other animals for example dogs and cats. Human mammary cell types generated. The inner luminal cells surrounded by basal myoepithelium. Not detected hepatitis b.

These cells are ideally suited to support the study of many fields including inflammation cancer gene regulation cell matrix interactions and also have application in toxicology testing and drug screening development. Primary human mammary epithelial cells cryopreserved at the end of the 6th culture. Review of the human mammary epithelial cell hmec culture system last revised january 2003 procedures. In these structures there are two main cell types.

Atcc primary cell solutions offers epithelial cells isolated from human breast bronchi trachea and small airways cornea prostate and kidneys. Breast cancer is the most common cancer in women and a leading cause of cancer related deaths for women worldwide. Various cell models have been developed to study breast cancer tumorigenesis metastasis and drug sensitivity. When epithelial cells become malignant become cancerous they form tumors that are referred to as carcinomas.

Atcc stands ready to support our customers needs during the coronavirus pandemic. The mcf10a human mammary epithelial cell line is a widely used in vitro model for studying normal breast cell function and transformation. Not detected hepatitis c. Epithelial cells are defined as cells or tissue of the epithelium a thin layer of tissue that covers or lines the surface of tubes or cavities within the body.

The majority of breast cancers originate in the lobular or ductal cells of the milk producing glands. Human mammary epithelial cells were obtained from a healthy individual undergoing reduction. Biology of the mammary gland provided by the national institute of health labarge lab.