Human Bone Marrow Stromal Cells

It is composed of hematopoietic cells marrow adipose tissue and supportive stromal cells in adult humans bone marrow is primarily located in the ribs vertebrae sternum and bones of the pelvis.

Human bone marrow stromal cells.

Adult bone marrow also contains stromal stem cells which contribute to the regeneration of several tissues such as bone cartilage muscle ligament tendon adipose tissue and marrow stroma 9 human bmscs have been identified and characterized and it has been shown that they support hematopoietic progenitors and secrete a number of. Human bone marrow stromal cells derived in acf medium catalog 70071 using the mesencult acf culture kit catalog 05449 differentiate to a adipocytes oil red o staining b chondrocytes alcian blue and nuclear fast red staining and c. The most common stromal cells include fibroblasts and pericytes the term stromal comes from latin stromat bed covering and ancient greek στρῶμα. Stromal cells are connective tissue cells of any organ for example in the uterine mucosa endometrium prostate bone marrow lymph node and the ovary they are cells that support the function of the parenchymal cells of that organ.

Sscs have been identified as pericytes cells on the abluminal side of marrow sinusoids and have demonstrated the ability to self renew. When autologous or allogeneic bmscs were added back to t c. Human bone marrow stromal cells cultured using the mesencult acf culture kit maintain multi lineage differentiation potential. In birds and mammals bone marrow is the primary site of new blood cell production or haematopoiesis.